Researchers from many UK universities have made several studies to see whether CBD can help in increasing the effectiveness of various antibiotics based on the bacteria type. The research team tried to track the membrane vesicles released from the bacteria both with and also without CBD.
They used cannabis and confirmed that CBD could affect the MVs numbers released and also the structure of those MVs that are released from bacteria.
That research project tried to test the CBD effects on different bacteria types with either thin or thick cell walls and found that CBD reduced the MVs released from the bacteria with thin cell walled. This significantly increased the effectiveness of bacteria-killing of such kind during the presence of any antibiotics.
After discovering this, the team then concluded that using CBD with a few specific antibiotics can be used to target any bacteria to become sensitive to any antibiotic treatment and also reduce antibiotic resistance.
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What the research has shown?
As we know, CBD is considered a non-psychoactive compound that is obtained from hemp and cannabis, because it never produces the high effect that regular marijuana is known for. So far, the FDA has allowed CBD only for the treatment of certain rare forms of seizure. However, people have started using CBD to treat many other kinds of health benefits.
In one research study, researchers had tried to look at the ability of CBD to kill bacteria. According to them, in every case, they found that CBD had almost similar potency that any common antibiotics have.
The researchers had tested the CBD by comparing some staphylococcus strains, which can cause various skin infection, and also streptococcus, which can cause strep throat.
With this, they tried to compare how effective CBD can be as compared to any common antibiotics, like vancomycin and daptomycin. They tried to look at how quickly CBD could kill the bacteria. They found that within 3 hours it could, that was quite fast. Vancomycin (Vancocin) generally kills after 6 – 8 hours.”
Also, they found CBD could disrupt the biofilm, where the goop layer around bacteria makes it a little more difficult for an antibiotic to kill.
Finally, various lab studies also showed that CBD is less likely as compared to present-day antibiotics to cause resistance. Researchers however think that CBD is often selective while choosing the bacteria type.
Researchers also found CBD effective against any gram-positive bacteria and not against gram-negative. Any gram-positive bacteria usually cause pneumonia and serious skin infections, among other conditions. While gram-negative bacteria may include salmonella that is found generally in undercooked foods or E. coli among other bacteria.
Also, in another study, which is still inconclusive where researchers tried to test topical CBD for treating mice a skin infection. It cut after 48 hours number of bacteria, but it could not clear the infection. However, that research is still ongoing.